FFPE Human Tissue A Complete Guide

FFPE Human Tissue: A Complete Guide

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Last Updated on December 31, 2023 by Emma White

As researchers and laboratories alike continue to push the boundaries in scientific discoveries, the important role of FFPE human tissue cannot be ignored. FFPE human tissue is a commonly used term in the medical and research world, and yet many are still unaware of what it is its uses, and why it is crucial for research. 

In this blog post, we will delve into the basics of FFPE human tissue and why it has become increasingly valuable as a resource. 

What is FFPE Human Tissue?

So, what exactly is FFPE human tissue? Frozen Formalin-Fixed Paraffin-Embedded (FFPE) tissue is a technique of preserving biological samples, wherein the tissue is first fixed with formalin and then embedded in paraffin wax before being sliced into thin sections. The FFPE technique allows researchers to store tissue samples for longer periods with minimal deterioration in the samples’ structural and chemical composition. These FFPE samples can be used for future research, especially in longitudinal studies.

How FFPE Human Tissue Samples Are Used

FFPE human tissue has several uses when it comes to research and developing scientific discoveries. One of the most common uses is in the development of biomarkers. The preservation of essential proteins and nucleic acids in FFPE human tissue enables their identification and analysis, which is often vital for understanding diseases’ pathogenesis.

Additionally, FFPE tissue has been used extensively in cancer research, as the primary material used for histopathology diagnoses. The technique has helped identify specific genetic and protein biomarkers that play a crucial role in cancer diagnosis, prognosis, and response to treatment.

The importance of FFPE tissue samples in research cannot be overstated. They have become instrumental in the study of various diseases, such as Alzheimer’s, heart disease, and various types of cancer. These tissue samples can provide researchers with much-needed insight into diseases’ mechanisms and progressions, enabling innovations in diagnosing, treating, and potentially curing such diseases.

Where Can You Get FFPE Human Tissue Samples?

If you’re a researcher looking for FFPE human tissue samples, several laboratories provide them. However, it’s essential to locate a reputable, reliable laboratory that can provide quality samples suitable for your research. You can browse various professional websites and directories to find a laboratory with an extensive collection of FFPE tissue samples. Additionally, selected hospitals provide human tissue biobanks, which are rich in FFPE samples, mainly from cancer patients.

Use FFPE Tissue to Further Your Research

In conclusion, FFPE human tissue is widely used in research, particularly in disease diagnosis and treatment. The ability to preserve tissue samples for long periods with minimal deterioration has provided researchers with massive insight into various diseases’ mechanisms and progressions. 

As such, FFPE human tissue has become an invaluable tool in research and development. If you’re a researcher or laboratory, you can find FFPE human tissue samples from various sources, including professional websites, directories, and selected hospitals’ biobanks. Using FFPE tissue samples can accelerate scientific discoveries and improve healthcare outcomes.